Search results for " Blood Vessels"
showing 4 items of 4 documents
Decellularized Saphena: Biologic Scaffold for 3D Cellular Growth
2016
A Fibrillar Biodegradable Scaffold for Blood Vessels Tissue Engineering
2012
In recent years there has been a growing interest for the development of tubular scaffolds employed to assist the replacement of small blood vessels. Materials designed for this purpose need to be biodegradable, have good mechanical properties and improve cell adhesion, proliferation and differentiation. To obtain biomaterials with these properties, electrospinning seems to be one of the most useful technique. Several biodegradable synthetic polymers or constituents of the extracellular matrix (ECM) have been electrospun showing optimal mechanical properties and biodegradability. However, such polymers are lacking in versatile chemical structure affordable to immobilize growth factors or ch…
Decidual endothelial cells express surface-bound C1q as a molecular bridge between endovascular trophoblast and decidual endothelium.
2008
This study was prompted by the observation that decidual endothelial cells (DECs), unlike endothelial cells (ECs) of blood vessels in normal skin, kidney glomeruli and brain, express surface-bound C1q in physiologic pregnancy. This finding was unexpected, because deposits of C1q are usually observed in pathologic conditions and are associated with complement activation. In the case of DECs, we failed to detect immunoglobulins and C4 co-localized with C1q on the cell surface. Surprisingly, DECs expressed mRNA for the three chains of C1q and secreted detectable level of this component in serum-free medium. The ability to synthesize C1q is acquired by DECs during pregnancy and is not shared by…
Influence of ocular aberrations on the diameter of retinal blood vessels
2011
Lower-order and higher-order ocular aberrations influence not only visual perception but also appearance of retinal images. We suggest that the diameter of blood vessels may differ for various patterns of aberrations based on how the maps of point spread functions are orientated to these vessels. We tested our hypothesis by a star chart simulation method and by using simulating aberrations in a real image of a living retina. We observed that broadening of the blood vessels due to ocular aberrations depends not only on the relative orientation of the wavefront but also on their actual width. The change in the diameter ratio is clinically significant and is comparable to changes in the arteri…